Dr. Jiwu Chen

Sports Medicine Specialist

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Knee injuries 7 min read 2026.06.10

Which graft is best for ACL reconstruction? Autograft vs allograft

ACL reconstruction uses a graft to create a new stabilizing ligament. Autograft, allograft, and synthetic ligaments each have different roles, and the best choice depends on age, sport goals, work demands, and knee condition.

Author: Dr. Jiwu Chen Medical review: 2026-06-10
ACL reconstructionGraft choiceAutograftAllograft

Why does ACL reconstruction need a graft?

After an anterior cruciate ligament, or ACL, tear is diagnosed and reconstruction is recommended, many patients ask: What ligament will be used? Will the surgeon take a tendon from my own body? Is a donated tendon better?

ACL reconstruction is not usually a simple repair of the torn ligament ends. Instead, a graft is used to create a new ACL-like structure that can restore knee stability.

Different grafts have different advantages and limitations. There is no single best graft for every patient, so the decision should reflect age, activity level, work demands, previous surgery, and the overall condition of the knee.

Why can’t a torn ACL simply be stitched back together?

Many people imagine that a torn ligament can simply be sutured end to end. For most complete ACL tears, however, the blood supply is limited and the knee keeps moving, so the torn ends usually do not heal reliably.

For this reason, ACL reconstruction remains the mainstream treatment for many complete ACL tears. A new tendon graft is used to replace the torn ACL and gradually remodel into a functional ligament-like structure.

What is a graft?

A graft is the new tissue used to reconstruct the ACL. After fixation, it gradually integrates with the bone and undergoes biological remodeling over several months before taking on the role of the ACL.

The grafts most commonly used in clinical practice are autografts and allografts. Synthetic ligaments may be considered in selected cases, but their routine use is more limited.

Autograft: the most common choice

An autograft uses the patient’s own tendon. It is one of the most common choices for ACL reconstruction, especially for younger patients, active patients, and people who want reliable long-term stability.

Hamstring tendon graft

The hamstring tendon is one of the most widely used ACL grafts worldwide. The surgeon takes part of the hamstring tendon from the inner side of the knee, prepares it, and uses it to reconstruct the ACL.

Advantages: smaller incision, less pain, less impact on daily activities, and mature rehabilitation protocols.

Possible limitations: early weakness of the back of the thigh or reduced knee flexion strength. With structured rehabilitation, most patients recover good function.

Bone-patellar tendon-bone graft

The bone-patellar tendon-bone graft, often called BTB, is another classic ACL graft. It uses the middle portion of the patellar tendon with small bone blocks at both ends, allowing relatively fast bone-to-bone healing.

Advantages: strong initial fixation, faster bone healing, and good long-term stability. Many elite athletes have used this graft.

Possible limitations: because tissue is taken from the front of the knee, anterior knee pain or discomfort is more common. This matters especially for patients whose work requires frequent kneeling.

Hamstring tendon or BTB: which is better?

This is one of the most common patient questions. Large bodies of research show that hamstring tendon and BTB autografts have broadly similar overall outcomes.

There is no clear major difference in knee stability, daily function, return to sport, or long-term clinical results for many patients. The more important differences are the types of postoperative discomfort and donor-site symptoms.

For this reason, surgeons usually choose based on the patient’s sport, work demands, and personal goals rather than assuming one graft is always more advanced. Clinical guidelines also regard hamstring tendon and BTB as recommended first-line autograft choices.

Allograft: no need to harvest your own tendon

An allograft comes from donated human tissue. Its main feature is that the surgeon does not need to take tendon from the patient’s own body, so surgical trauma can be smaller.

Potential advantages: shorter operative time, no additional harvest site, and less donor-site pain after surgery.

Possible uses: selected revision surgeries, multi-ligament knee injuries, or cases where the patient does not have enough suitable autograft tissue.

Why is allograft not always recommended for young patients?

Although allograft has advantages, studies have found a relatively higher risk of graft failure in young and highly active patients.

Therefore, many sports medicine centers internationally still prioritize autograft for young patients with high athletic demands. Clinical guidelines similarly recommend considering autograft first in most ACL reconstructions, with allograft mainly reserved for selected situations.

Are synthetic ligaments suitable for everyone?

Synthetic ligaments have attracted attention in recent years. Their potential advantage is faster restoration of mechanical stability and, in theory, earlier rehabilitation.

However, long-term evidence remains limited. Some studies have reported problems such as reinjury, synovitis, joint effusion, and degenerative changes.

For most first-time ACL reconstruction patients, synthetic ligaments are not the routine first choice and should be considered carefully according to the specific case.

How does the doctor help choose?

These factors together determine which graft is most appropriate. The goal is not to choose the newest or most expensive material, but the graft that best supports the patient’s stability needs, rehabilitation goals, and long-term activity plan.

Age and general physical condition.

Whether the patient is a professional or high-level athlete.

Which sports the patient hopes to return to.

Work demands, especially frequent kneeling.

Whether the patient has had previous ACL surgery.

Whether there are multi-ligament injuries.

Whether enough suitable autograft tissue is available.

All content is for medical education only and cannot replace an in-person medical evaluation or an individualized treatment plan.

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